Histone Core Phosphorylation Regulates DNA Accessibility
نویسندگان
چکیده
منابع مشابه
Histone core phosphorylation regulates DNA accessibility 1 Histone Core Phosphorylation Regulates DNA Accessibility
Nucleosome unwrapping dynamics provide transient access to the complexes involved in DNA transcription, repair and replication, while regulation of nucleosome unwrapping modulates occupancy of these complexes. Histone H3 is phosphorylated at Tyrosine 41 (H3Y41ph) and Threonine 45 (H3T45ph). H3Y41ph is implicated in regulating transcription, while H3T45ph is involved in DNA replication and apopt...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2015
ISSN: 0021-9258
DOI: 10.1074/jbc.m115.661363